Ketotifen | Prosma
Overdose symptoms: confusion, drowsiness, headache, slow heart rate, respiratory depression; management includes gastric lavage or supportive care
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Prosma contains Ketotifen, which has anti-allergic and antihistamine properties. It functions similarly to sodium cromoglycate for the prevention of asthma and exhibits strong anti-anaphylactic effects. Ketotifen stabilizes mast cells and inhibits histamine reactions, effectively reducing the frequency, severity, and duration of asthma attacks over time. Clinical trials have shown that long-term use can allow for a reduction in corticosteroids or bronchodilators. However, Ketotifen does not stop ongoing asthma attacks, and its full prophylactic effect may take several weeks to develop.
Drowsiness, mild dizziness, dry mouth (usually resolves after a few days)
Adults
1 mg twice daily with food
May increase to 2 mg twice daily in severe cases
Children above 3 years
1 mg twice daily with food
For those sensitive to sedation, start with 0.5–1 mg at night for the first few days or as directed by a physician
Elderly
Same as adult dose unless otherwise advised
Avoid combining Prosma with oral antidiabetic drugs due to potential reversible platelet count reduction
May enhance the effects of sedatives, hypnotics, antihistamines, and alcohol
Not recommended due to lack of established safety, though no teratogenic effects have been reported
Store in a cool, dry place, protected from light
Keep out of reach of children
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